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KMID : 0870420150190010006
Korean Journal of Hepato-Biliary-Pancreatic Surgery
2015 Volume.19 No. 1 p.6 ~ p.10
Gallbladder perforation: a single center experience of 32 cases
Gunasekaran Gopalakrishnan

Naik Debasis
Gupta Ashwani
Bhandari Vimal
Kuppusamy Manigandan
Kumar Gaind
Chishi Niuto S
Abstract
Backgrounds/Aims: Gallbladder perforation is a rare but potentially fatal disease. We herein present our clinical experi-ence in diagnosis and management of 32 cases of gallbladder perforation.

Methods: This retrospective study was con-ducted with inclusion of all cases of gallbladder perforation that presented to our hospital from January 2012 to November 2014. Cases of traumatic gallbladder perforation and patients younger than 12 years of age were excluded from this study.

Results: This study included 32 patients (13 males and 19 females). The mean age of patients was 55.9 years. Gallbladder perforation was most common in the 5th and 6th decade of life. The mean age of patients with type I, II, and III gallbladder perforation was 57.0 years, 57.6 years, and 49.8 years, respectively. The most com-mon site of perforation was the fundus, followed by the body and Hartmann¡¯s pouch (24 : 5 : 2). Most of the type I gallbladder perforations were diagnosed intraoperatively, type II gallbladder perforations were diagnosed by enhanced abdominal computed tomography, and type III gallbladder perforations were diagnosed during laparoscopic chol-ecystectomy converted to open cholecystectomy for cholelithiasis. Mortality was highest in patients with type I gall-bladder perforation. The mean hospital stay was 10.1 days, 6.4 days, and 9.2 days in patients with type I, II, and III gallbladder perforation, respectively. The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case.

Conclusions: Gallbladder perforation represents a special diag-nostic and surgical challenge. Appropriate classification and management are essential.
KEYWORD
Gallbladder perforation, Acute cholecystitis, Cholecysto-enteric fistula, Hole sign, Percutaneous catheter drainage
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